Web Reference: In this review, we summarise the recent advances in our understanding of the formation of the germ layers in Xenopus laevis. Feb 1, 2006 · Despite this great success in early development, research on organogenesis in Xenopus has lagged behind the mouse. However, recent technical advances now make Xenopus amenable for studies on later development, including organogenesis. Xenopus eggs were injected in the animal hemisphere with VegT mRNA and animal caps isolated from blastulae. Control caps only form epidermis, while VegT injected caps also form endoderm and mesoderm. This demonstrates that VegT is sufficient for the formation of both of these germ layers.
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