Web Reference: Apr 25, 2022 · What is the integumentary system? Your integumentary system is your body’s outer layer. It’s made up of your skin, nails, hair and the glands and nerves on your skin. Your integumentary system acts as a physical barrier — protecting your body from bacteria, infection, injury and sunlight. Jan 24, 2026 · The integumentary system comprises several appendages derived from the epidermis, but they are primarily located in the dermis. These appendages, including cutaneous glands, hair, hair follicles, and nails, play important roles in protection, thermoregulation, sensation, and skin maintenance. Dec 14, 2025 · This article digs into the specifics about each part of the integumentary system, exactly what it does, how it interacts with other body systems, and some of the medical conditions that can affect it.
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