Web Reference: Sugars not only constitute a core part of our diet but also act as information molecules delivering key messages inside the body. These carbohydrates, also called glycans, are predominantly located on the surface of our cells and relay data about the cell’s health status. In this Front Row lecture, Scripps Research associate professor Mia Huang will share the innovative tools her lab is using to decode the language of glycans. “Ok, so they are everywhere, but does it mean they are important?” “Ok, so glycans are everywhere, and they seem to be changing in health and disease. How come we haven’t heard about them before?” Joeh et al., Mapping glycan-mediated galectin-3 interactions by live cell proximity labeling. PNAS (2020) 117:27329.
YouTube Excerpt: Sugary molecules called glycans encapsulate our cells, serving as beacons to direct key biological activities, from tissue ...
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