Web Reference: Here we review recent efforts in continuous unit operations, integrated processes, and process analytical technologies (PATs) that facilitate the implementation of continuous biomanufacturing, particularly of monoclonal antibodies (mAbs). Dec 1, 2022 · This review covers recent advances in continuous processing over the last two years for biopharmaceutical production. Perfusion, also called continuous processing, involves continuously removing cell culture from the bioreactor and replacing it with fresh media, allowing for simultaneous nutrient supply, waste removal, and product harvesting.
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