Web Reference: Our current testing algorithm for laboratory diagnosis of C. difficile disease utilizes an Enzyme Immunoassay (EIA) for detection of Toxin and GDH (a non-specific marker for C. difficile) followed by PCR assay for detection of Toxin gene if Tox-GDH+ by EIA. Multistep CDI test algorithms include a sensitive stool screening test such as a nucleic acid amplification test (NAAT) or glutamate dehydrogenase (GDH) antigen testing and a more specific test, enzyme immunoassay (EIA) for C. difficile toxin A and B May 14, 2021 · The first test, the C. difficile PCR, is a very sensitive test. C diff PCR(+) means the sample carries C. difficile organisms with the genetic material capable of producing toxin.
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