Web Reference: Description: In Lecture 9, we explore the realm of "Space-Efficient Sequence Alignment." Join us as we journey through techniques that streamline memory usag... Combining the “forward” and “reverse” DP using a divide and conquer technique, we can compute the optimal solution (not just the score) in linear space. This still only takes O(nm) time; constant factor more work than the “forward”-only algorithm. Can we do better in practice? In this lecture we continue the discussion on aligning two sequences. We rst describe a linear-space align-ment, then discuss more general penalties for the linear gap penalty model.
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