Web Reference: Thus, the Covarrubias laboratory will explore how NAD consuming and biosynthetic pathways are altered during these disease states, the biological mechanisms in which altered NAD levels impact metabolism, gene expression and cell biology, and explore NAD metabolism as a potential therapeutic target. Covarrubias is a macrophage biologist with expertise in immuno-metabolism, and how inflammation and metabolism are integrated to regulate metabolic health and disease states including aging. To further understand senescent macrophage biology and their role in inflammaging, Dr. Covarrubias developed an in vitro system to grow senescent macrophages.
YouTube Excerpt: May 2014 — In our video series "Why Public Health?" we ask Harvard School of Public Health students and alumni to talk about ...
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